Pulmonology

N95 masks increase brain blood velocity and parasympathetic outflow, yet worsen orthostatic symptoms in a healthy cohort

PMCID: PMC12177107 PMID: 40534183 DOI: 10.14814/phy2.70402 Journal: Physiological reports Publication Date: 2025-6-18 Authors: Pereira TJ, Edgell H Key Points * Mask wearing increased systolic cerebral blood flow but paradoxically worsened orthostatic intolerance symptoms * Total Vanderbilt Orthostatic Symptom Score increased from 12 to 20 during masked trials (p=0.

Pulmonology

Diagnostic Use of CCR3, CD63, CD203c and FcεRIα on Blood Leukocytes of Allergic Asthma and Combined Allergic Rhinitis and Asthma Syndrome

PMCID: PMC12176697 PMID: 40534099 DOI: 10.1111/jcmm.70594 Journal: Journal of cellular and molecular medicine Publication Date: 2025-6-18 Authors: Wang J, Zhan M, Gu F, Zhang H, Xie H, et al. Key Points * CCR3+ cell numbers and marker expressions are significantly altered in allergic asthma and allergic rhinitis patients

Pulmonology

Admission rate for bronchiolitis of newborns and infants in Italian neonatal intensive care units in 2021: a survey of the Italian Society of Neonatology - Intensive Care of Early Childhood Study Group

PMCID: PMC12175376 PMID: 40528201 DOI: 10.1186/s13052-025-01977-x Journal: Italian journal of pediatrics Publication Date: 2025-6-17 Authors: Decembrino N, Leonardi R, Fedeli T, Conte L, Distefano C, et al. Key Points * NICUs are emerging as critical alternative care centers during PICU bed shortages, particularly during RSV epidemics * 67% response rate

Emergency_Medicine

Tracheostomy in COVID-19: A retrospective cohort study of outcomes and mortality predictors in a specialized infectious disease hospital in Brazil

PMCID: PMC12176168 PMID: 40531975 DOI: 10.1371/journal.pone.0326531 Journal: PloS one Publication Date: 2025-6-18 Authors: Accetta AF, Medeiros DM, Diniz Ribeiro MP, Cardoso SW, Ferreira Tavares IC, et al. Key Points * 68% mortality rate among COVID-19 patients undergoing tracheostomy, emphasizing the severity of respiratory complications * Patients over 60

Pulmonology

Multicenter clinical trial for the treatment of obstructive sleep apnea with a non-permanent orthodontic intraoral device in children

PMCID: PMC12174215 PMID: 40526156 DOI: 10.1007/s00431-025-06254-x Journal: European journal of pediatrics Publication Date: 2025-6-17 Authors: Kushida CA, Stevens J, Bennett M, Heit T, Klemp D, et al. Key Points * First FDA-cleared non-permanent orthodontic device specifically designed for pediatric OSA treatment * 61.7% of participants achieved >50% AHI

Pulmonology

Risk Factors and Long‐Term Prognosis for Coinfection of Nontuberculous Mycobacterial Pulmonary Disease and Chronic Pulmonary Aspergillosis: A Multicentre Observational Study in Japan

PMCID: PMC12178108 PMID: 40536274 DOI: 10.1111/myc.70083 Journal: Mycoses Publication Date: 2025-6-19 Authors: Tanaka Y, Ide S, Takazono T, Takeda K, Iwanaga N, et al. Key Points * CPA coinfection occurs in 3.5% of NTM-PD patients, with Aspergillus fumigatus being the most common causative species * Male sex, COPD,

Pathology

Inflammatory cells and remodeling in bronchial biopsies from COPD patients and controls

PMCID: PMC12173230 PMID: 40526700 DOI: 10.1371/journal.pone.0326267 Journal: PloS one Publication Date: 2025-6-17 Authors: Eagan TM, Nielsen R, Haaland I, Husebø GR, Lehmann S, et al. Key Points * COPD patients exhibit increased macrophage and eosinophil populations in bronchial submucosa * GOLD stages I/II demonstrated higher eosinophil counts

Emergency_Medicine

Clinical characteristics and resource utilization of emergency department patients with obstructive sleep apnea

PMCID: PMC12173181 PMID: 40526732 DOI: 10.1371/journal.pone.0326194 Journal: PloS one Publication Date: 2025-6-17 Authors: Sun M, Zhang X, Liu YC, Pei J, Fan H, et al. Key Points * OSA patients represent a distinct, high-acuity subgroup in emergency departments, with unique demographic and clinical characteristics * Adjusted odds ratios

Pulmonology

The effect of target transpulmonary driving pressure values on mortality in ARDS patients: A retrospective study based on the MIMIC-IV database

PMCID: PMC12176163 PMID: 40531833 DOI: 10.1371/journal.pone.0326060 Journal: PloS one Publication Date: 2025-6-18 Authors: Liu N, Zhang Q, Wang H, Ding R, Geng X, et al. Key Points * Transpulmonary driving pressure >12.5 cmH2O is associated with increased mortality in ARDS patients * Targeted TPDP management reduced

Pulmonology

Assessment of ventilation heterogeneity in severe asthma using phase‐resolved functional lung magnetic resonance imaging

PMCID: PMC12177108 PMID: 40534189 DOI: 10.14814/phy2.70423 Journal: Physiological reports Publication Date: 2025-6-18 Authors: Foo CT, Langton D, Donovan GM, Thompson BR, Noble PB, et al. Key Points * PREFUL MRI revealed significantly higher ventilation defect percentages in severe asthma patients (19.9% vs. 1.9% in healthy volunteers)

Cardiology

Nicotine Exacerbates Arrhythmogenesis in Rabbit Right Ventricular Outflow Tract Triggered by Chronic Obstructive Pulmonary Disease

PMCID: PMC12176695 PMID: 40533933 DOI: 10.1111/jcmm.70664 Journal: Journal of cellular and molecular medicine Publication Date: 2025-6-18 Authors: Chan C, Lin F, Chen Y, Higa S, Chen S, et al. Key Points * COPD and nicotine independently increase ventricular tachycardia risk, with nicotine exacerbating arrhythmogenic potential * 89% of nicotine-treated

Pulmonology

N95 masks increase brain blood velocity and parasympathetic outflow, yet worsen orthostatic symptoms in a healthy cohort

PMCID: PMC12177107 PMID: 40534183 DOI: 10.14814/phy2.70402 Journal: Physiological reports Publication Date: 2025-6-18 Authors: Pereira TJ, Edgell H Key Points * Mask wearing increased systolic cerebral blood flow but paradoxically worsened orthostatic intolerance symptoms * Total Vanderbilt Orthostatic Symptom Score increased from 12 to 20 during masked trials (p=0.