Psychiatry - CurrentMed (Page 3)

Psychiatry

Sexual dysfunction and other prolactin-related side effects of antipsychotic drugs in schizophrenia: Protocol for a systematic review with single-arm, pairwise, and network meta-analyses of randomized controlled trials and non-randomized studies

PMCID: PMC12138325 PMID: 40474917 DOI: 10.12688/f1000research.154742.1 Journal: F1000Research Publication Date: 2025-6-19 Authors: Schneider-Thoma J, Dong S, Kim DD, Efthimiou O, Siafis S, et al. Key Points * Sexual dysfunctions are prevalent in schizophrenia patients, potentially impacting treatment adherence and quality of life * The study will comprehensively analyze

Psychiatry

Transcranial Electrical Stimulation in Treatment of Depression: A Systematic Review and Meta-Analysis

PMCID: PMC12177679 PMID: 40531534 DOI: 10.1001/jamanetworkopen.2025.16459 Journal: JAMA network open Publication Date: 2025-6-18 Authors: Ren C, Pagali SR, Wang Z, Kung S, Boyapati RB, et al. Key Points * tDCS combined with medication showed significant improvement in depression with comorbid conditions * tACS demonstrated improved depressive symptoms in

Psychiatry

A one-arm pilot trial of a telehealth CBT-based group intervention targeting transdiagnostic risk for emotional distress

PMCID: PMC12176177 PMID: 40531853 DOI: 10.1371/journal.pone.0303131 Journal: PloS one Publication Date: 2025-6-18 Authors: Flynt S, Cho GY, Koscinski B, Accorso C, Knapp A, et al. Key Points * Telehealth-delivered modular CBT intervention shows potential for addressing transdiagnostic mental health risk factors * 85% participant retention rate and high

Psychiatry

Understanding Youth Online Experiences and Mental Health: Development and Validation of the Digital Activity and Feelings Inventory (DAFI)

PMCID: PMC12173090 PMID: 40526710 DOI: 10.1002/mpr.70028 Journal: International journal of methods in psychiatric research Publication Date: 2025-6-17 Authors: Katarzyna K, Jake B, Aja M, Mariya S, Iqra A, et al. Key Points * Social comparison and negative self-reactions were stronger predictors of mental health outcomes than total screen

Psychiatry

Novel tools for comparing the architecture of psychopathology between neurogenetic disorders: An application to X- versus Y-chromosome aneuploidy effects in males

PMCID: PMC12180508 PMID: 40525963 DOI: 10.1017/S0033291725000765 Journal: Psychological medicine Publication Date: 2025 Authors: Larsen IG, Liu S, Schaffer L, Rau S, Ajumobi T, et al. Key Points * Proactive aggression and social problems exhibit distinctly different correlation patterns between XXY/KS and XYY syndromes * No statistically significant differences were

Immunology

Research Progress on Inflammation and Immune Dysregulation in PTSD

PMCID: PMC12171638 PMID: 40525295 DOI: 10.1002/brb3.70633 Journal: Brain and behavior Publication Date: 2025-6-17 Authors: Yang L, Lu J, Zhao Z, Zhang Z, Yang W, et al. Key Points * PTSD is characterized by significant immune system dysregulation with consistent pro-inflammatory cytokine elevations * Multiple studies demonstrated increased inflammatory markers

Psychiatry

Mental health and health-related quality of life among adults with osteoarthritis: A national population-based study

PMCID: PMC12176145 PMID: 40531897 DOI: 10.1371/journal.pone.0325780 Journal: PloS one Publication Date: 2025-6-18 Authors: Alwhaibi M, Alhawassi TM Key Points * Comorbid depression and anxiety significantly reduce mental health-related quality of life in OA patients * 9.9% of OA patients experience both depression and anxiety, with the most

Psychiatry

Experiential Avoidance as a Transdiagnostic Mediator in the Relationship Between Intolerance of Uncertainty, Maladaptive Perfectionism, and Psychiatric Symptoms: Structural and Causal Mediation Analyses in a Clinical Sample

PMCID: PMC12178104 PMID: 40536179 DOI: 10.1002/cpp.70102 Journal: Clinical psychology & psychotherapy Publication Date: 2025-6-19 Authors: Gerdan G, Salcioglu E Key Points * Experiential avoidance fully mediates the relationship between intolerance of uncertainty, maladaptive perfectionism, and psychiatric symptoms * EA explained 1.254 standard deviations in the relationship between intolerance

Psychiatry

Relationship between spiritual well-being with anxiety and depression among cancer patients

PMCID: PMC12176229 PMID: 40531814 DOI: 10.1371/journal.pone.0322923 Journal: PloS one Publication Date: 2025-6-18 Authors: Vakili Sadeghi M, Tehrani MA, Pasha H, Hamidia A, Nabipour M, et al. Key Points * Spiritual well-being significantly and negatively predicts anxiety (β = -0.154, P < 0.001) and depression (β = -0.

Pharmacology

Comparative effectiveness of interventions to facilitate deprescription of benzodiazepines and other sedative hypnotics: systematic review and meta-analysis

PMCID: PMC12171951 PMID: 40527546 DOI: 10.1136/bmj-2024-081336 Journal: BMJ (Clinical research ed.) Publication Date: 2025 Authors: Zeraatkar D, Nagraj SK, Ling M, Jassal T, Kirsh S, et al. Key Points * Patient education and pharmacist-led interventions showed the most promise in facilitating BSH discontinuation * Low-certainty evidence suggests 144 more patients

Neurology

Longitudinal assessment of cognitive function in testicular cancer patients prior to orchiectomy and 9 months later and associations with tumor markers

PMCID: PMC12174274 PMID: 40526183 DOI: 10.1007/s00520-025-09637-w Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer Publication Date: 2025-6-17 Authors: Højris NF, Frederiksen Y, Agerbæk M, Nielsen SH, Holt M, et al. Key Points * Low prevalence of cognitive impairment (10.3% pre-surgery,

Psychiatry

Longitudinal Suicide Risk in Children and Adolescents With Attention Deficit and Hyperactivity Disorder: A Systematic Review and Meta‐Analysis

PMCID: PMC12177204 PMID: 40534226 DOI: 10.1002/brb3.70618 Journal: Brain and behavior Publication Date: 2025-6-18 Authors: Garas P, Takacs ZK, Balázs J Key Points * Individuals with ADHD have a 3-4 times higher risk of suicidal behaviors compared to non-ADHD populations * Suicide risk varies significantly across ADHD subtypes, with combined