Cardiology - CurrentMed (Page 2)

Cardiology

Atrial dysfunction: a contrast-free marker for HFpEF in obese diabetics—insights from comprehensive CMR and serum biomarker analyses

PMCID: PMC12175437 PMID: 40533773 DOI: 10.1186/s12933-025-02808-3 Journal: Cardiovascular diabetology Publication Date: 2025-6-18 Authors: Beyer RE, Müller ML, Doeblin P, Werhahn SM, Chiribiri A, et al. Key Points * Left atrial function metrics provide the most reliable CMR-based differentiation of HFpEF from similar clinical conditions * LA maximum volume showed the

Cardiology

The role of transient receptor potential melastatin channels in compressive force‐induced contraction of primary cardiac pericytes

PMCID: PMC12172562 PMID: 40526043 DOI: 10.14814/phy2.70396 Journal: Physiological reports Publication Date: 2025-6-17 Authors: Methner C, Cilento E, Cao Z, Iliff J, Mishra A, et al. Key Points * Cardiac pericytes possess mechanosensitive TRPM4 and TRPM7 channels that contribute to microvascular dysfunction during acute myocardial infarction * TRPM4 inhibition reduced

Anesthesiology

Sedation and analgesia in post-cardiac arrest care: a post hoc analysis of the TTM2 trial

PMCID: PMC12175406 PMID: 40528173 DOI: 10.1186/s13054-025-05461-0 Journal: Critical care (London, England) Publication Date: 2025-6-17 Authors: Ceric A, Dankiewicz J, Cronberg T, Düring J, Moseby-Knappe M, et al. Key Points * Higher propofol doses (Q3: 100.7-153.6 mg/kg) significantly improved functional outcomes and survival * Fentanyl and remifentanil use

Cardiology

Nicotine Exacerbates Arrhythmogenesis in Rabbit Right Ventricular Outflow Tract Triggered by Chronic Obstructive Pulmonary Disease

PMCID: PMC12176695 PMID: 40533933 DOI: 10.1111/jcmm.70664 Journal: Journal of cellular and molecular medicine Publication Date: 2025-6-18 Authors: Chan C, Lin F, Chen Y, Higa S, Chen S, et al. Key Points * COPD and nicotine independently increase ventricular tachycardia risk, with nicotine exacerbating arrhythmogenic potential * 89% of nicotine-treated