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Pulmonology

Risk Factors and Long‐Term Prognosis for Coinfection of Nontuberculous Mycobacterial Pulmonary Disease and Chronic Pulmonary Aspergillosis: A Multicentre Observational Study in Japan

PMCID: PMC12178108 PMID: 40536274 DOI: 10.1111/myc.70083 Journal: Mycoses Publication Date: 2025-6-19 Authors: Tanaka Y, Ide S, Takazono T, Takeda K, Iwanaga N, et al. Key Points * CPA coinfection occurs in 3.5% of NTM-PD patients, with Aspergillus fumigatus being the most common causative species * Male sex, COPD,

By Ethan Littlefield

Oncology

Impact of multikinase inhibitors in reshaping the treatment of advanced gastroenteropancreatic neuroendocrine tumors

PMCID: PMC12177888 PMID: 40392078 DOI: 10.1530/ERC-25-0052 Journal: Endocrine-related cancer Publication Date: 2025-6-18 Authors: Siebenhüner AR, Refardt J, Nicolas GP, Kaderli R, Walter MA, et al. Key Points * MKIs represent a significant advancement in GEP-NET treatment, offering improved progression-free survival across multiple tumor subtypes * Median PFS improvements range from

By Ethan Littlefield

Surgery

Understanding and acceptance of open, laparoscopic, and robotic surgery among nursing students: implications for educational curricula based on a mixed-methods study

PMCID: PMC12176940 PMID: 40533608 DOI: 10.1007/s11701-025-02373-7 Journal: Journal of robotic surgery Publication Date: 2025-6-18 Authors: Özkan E, Çankaya A, Özsoy H Key Points * Nursing students showed varying levels of surgical technology knowledge, with mean knowledge scores of 5.26 for open surgery, 2.49 for laparoscopic surgery, and

By Ethan Littlefield

Oncology

Outcomes Following Transoral Laser Microsurgery for T1b and T2a Glottic Squamous Cell Carcinoma With and Without Anterior Commissure Involvement: A Retrospective Chart Review

PMCID: PMC12177246 PMID: 40530452 DOI: 10.1177/19160216251348424 Journal: Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale Publication Date: 2025-6-18 Authors: Patel D, Taylor V, MacKay C, den Besten C, Rigby MH, et al. Key Points * TLM demonstrates comparable oncological outcomes

By Ethan Littlefield

Oncology

The efficacy and therapy management of nab-paclitaxel in the real-world setting for patients with advanced breast cancer – the SERAPHINA study

PMCID: PMC12178961 PMID: 40536732 DOI: 10.1007/s00432-025-06246-2 Journal: Journal of cancer research and clinical oncology Publication Date: 2025-6-19 Authors: Schneeweiss A, Fasching PA, Thill M, van Mackelenbergh M, Marme F, et al. Key Points * Nab-paclitaxel demonstrated consistent efficacy across multiple treatment lines in advanced breast cancer * Median progression-free survival

By Ethan Littlefield

Oncology

Myeloid‐Derived LGALS9‐P4HB Immune Interaction Promotes Metastasis in Gastric Cancer Through Enhanced Cell Proliferation and Lipid Metabolism

PMCID: PMC12176694 PMID: 40534096 DOI: 10.1111/jcmm.70661 Journal: Journal of cellular and molecular medicine Publication Date: 2025-6-18 Authors: Zhu X, Zhang Y, Yu A, Xiao X Key Points * Myeloid cell-derived LGALS9 and epithelial cell P4HB interaction is a previously uncharacterized mechanism driving gastric cancer metastasis * Pharmacological P4HB inhibitors

By Ethan Littlefield

Pharmacology

Comparative effectiveness of interventions to facilitate deprescription of benzodiazepines and other sedative hypnotics: systematic review and meta-analysis

PMCID: PMC12171951 PMID: 40527546 DOI: 10.1136/bmj-2024-081336 Journal: BMJ (Clinical research ed.) Publication Date: 2025 Authors: Zeraatkar D, Nagraj SK, Ling M, Jassal T, Kirsh S, et al. Key Points * Patient education and pharmacist-led interventions showed the most promise in facilitating BSH discontinuation * Low-certainty evidence suggests 144 more patients

By Ethan Littlefield

Immunology

Monoclonal humanized monovalent antibody blocking therapy for anti-NMDA receptor encephalitis

PMCID: PMC12174348 PMID: 40527893 DOI: 10.1038/s41467-025-60628-1 Journal: Nature communications Publication Date: 2025-6-17 Authors: Kanno A, Kito T, Maeda M, Yamaki S, Amano Y, et al. Key Points * First monovalent antibody designed to specifically block pathogenic NMDAR autoantibodies without receptor dysfunction * Demonstrated 74% reversal of NMDAR internalization at 2.

By Ethan Littlefield