CurrentMed (Page 5)

Psychiatry

A one-arm pilot trial of a telehealth CBT-based group intervention targeting transdiagnostic risk for emotional distress

PMCID: PMC12176177 PMID: 40531853 DOI: 10.1371/journal.pone.0303131 Journal: PloS one Publication Date: 2025-6-18 Authors: Flynt S, Cho GY, Koscinski B, Accorso C, Knapp A, et al. Key Points * Telehealth-delivered modular CBT intervention shows potential for addressing transdiagnostic mental health risk factors * 85% participant retention rate and high

Neurology

The neurobiological foundation of effective repetitive transcranial magnetic brain stimulation in Alzheimer's disease

PMCID: PMC12175030 PMID: 40530618 DOI: 10.1002/alz.70337 Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association Publication Date: 2025-6-18 Authors: Antonioni A, Martorana A, Santarnecchi E, Hampel H, Koch G Key Points * rTMS demonstrates comprehensive neurobiological modulation in AD, targeting synaptic, molecular, and

Pharmacology

[18F]FET PET-Guided management of pseudoprogression in glioblastoma (FET POPPING): the study protocol for a diagnostic randomized clinical trial

PMCID: PMC12175455 PMID: 40528226 DOI: 10.1186/s13063-025-08921-8 Journal: Trials Publication Date: 2025-6-17 Authors: Ruijters VJ, Snijders TJ, van der Pol JA, van de Giessen EM, Niers JM, et al. Key Points * First comprehensive randomized trial investigating FET PET's utility in differentiating pseudoprogression from true tumor progression in

Endocrinology

Placental inflammation is increased in gestational diabetes mellitus: The role of inflammasome NLRP-3 and chemokine scavenger decoy receptor D6

PMCID: PMC12173348 PMID: 40526637 DOI: 10.1371/journal.pone.0326087 Journal: PloS one Publication Date: 2025-6-17 Authors: Onori M, Beneduce G, Colella F, Lucchetti D, Policola C, et al. Key Points * GDM is characterized by elevated pro-inflammatory cytokines and increased NLRP-3 inflammasome expression * Statistically significant differences observed: CCL-2 (p <

Immunology

Measuring cytokines in Eurasian tundra reindeer (Rangifer tarandus tarandus) with a bovine bead-based multiplex immunoassay and real-time PCR

PMCID: PMC12175305 PMID: 40533814 DOI: 10.1186/s13028-025-00819-4 Journal: Acta veterinaria Scandinavica Publication Date: 2025-6-18 Authors: Frøvoll TL, Lybeck K, Lund H, Makvandi-Nejad S, Grimholt U, et al. Key Points * First comprehensive evaluation of cytokine detection methods specifically for reindeer immunology * Successfully measured inflammatory cytokines using a cross-species multiplex assay,

Oncology

N6-methyladenosine-modified GPX2 impacts cancer cell stemness and TKI resistance through regulating of redox metabolism

PMCID: PMC12177039 PMID: 40533443 DOI: 10.1038/s41419-025-07764-0 Journal: Cell death & disease Publication Date: 2025-6-18 Authors: Yang X, Yu L, Shao M, Yang H, Qi K, et al. Key Points * GPX2 serves as a critical mediator of EGFR-TKI resistance in NSCLC by modulating cellular redox balance * Knockdown of GPX2

Infectious_Disease

Influenza Epidemiology in Finland During and After the COVID‐19 Pandemic: Surveillance Data Analysis (2019–2024)

PMCID: PMC12174475 PMID: 40528677 DOI: 10.1111/irv.70131 Journal: Influenza and other respiratory viruses Publication Date: 2025-6-17 Authors: Baum U, Ikonen N, Luomala O, Poukka E, Leino T, et al. Key Points * COVID-19 containment measures effectively suppressed influenza transmission, creating a unique epidemiological "natural experiment" * Vaccine effectiveness

Endocrinology

Cardiac structure and function across the continuum of glucose metabolism

PMCID: PMC12172345 PMID: 40526029 DOI: 10.14814/phy2.70429 Journal: Physiological reports Publication Date: 2025-6-17 Authors: Grönlund T, Kaikkonen K, Junttila MJ, Ukkola O, Kerkelä R, et al. Key Points * Higher HbA1c levels within normal and prediabetic ranges are associated with decreased myocardial contractility * Proportion of subjects with abnormal global

Gastroenterology

The Effect of Postoperative Antithrombin Supplementation on the Inflammatory and Coagulation Status of a Surgically Treated Patient With a Malignant Tumor in the Small Pelvis—Case Series

PMCID: PMC12177226 PMID: 40534446 DOI: 10.1002/cnr2.70260 Journal: Cancer reports (Hoboken, N.J.) Publication Date: 2025-6-19 Authors: Lazović R, Šarenac O Key Points * Antithrombin supplementation can effectively normalize coagulation and inflammatory responses in complex surgical patients * Observed 50-70% reduction in inflammatory markers (IL-6, CRP) within 4 postoperative days

Surgery

Higher revision and secondary surgery rates after ACL reconstruction in athletes under 16 compared to those over 16: a case-control study

PMCID: PMC12172342 PMID: 40528219 DOI: 10.1186/s13018-025-05935-5 Journal: Journal of orthopaedic surgery and research Publication Date: 2025-6-17 Authors: Tátrai M, Halasi T, Tállay A, Tátrai A, Karácsony AF, et al. Key Points * Adolescent athletes under 16 have a 44% total secondary surgery rate compared to 21% in older patients

Radiology

Using radiomics model for predicting extraprostatic extension with PSMA PET/CT studies: a comparative study with the Mehralivand grading system

PMCID: PMC12177976 PMID: 40533824 DOI: 10.1186/s40644-025-00894-w Journal: Cancer imaging : the official publication of the International Cancer Imaging Society Publication Date: 2025-6-18 Authors: Bian L, Liu F, Peng Y, Liu X, Li P, et al. Key Points * Radiomics model using PSMA PET/CT demonstrates superior EPE prediction compared to