Pharmacology
PMCID: PMC12178312 PMID: 40536902 DOI: 10.1002/vms3.70416 Journal: Veterinary medicine and science Publication Date: 2025-6-19 Authors: Chen C, A‐ga YB, Kuang X, Li Y, Xiang R, et al. Key Points * Palmatine demonstrates rapid absorption and distribution in Partridge Shank chickens following intramuscular administration * Peak plasma concentration of
Obstetrics_Gynecology
PMCID: PMC12182189 PMID: 40527566 DOI: 10.1136/bmjopen-2024-094607 Journal: BMJ open Publication Date: 2025 Authors: Whybrow R, Chappell L, Webster L, Girling J, Brown H, et al. Key Points * Women with chronic hypertension experienced limited involvement in birth planning, with only 34.6% of case notes documenting patient participation * Caesarean
Neurology
PMCID: PMC12175199 PMID: 40530831 DOI: 10.1002/hbm.70263 Journal: Human brain mapping Publication Date: 2025-6-18 Authors: Cheng Z, Yang L, Li M, Zhang Q, Li J, et al. Key Points * T2DM patients showed significantly higher iron deposition in caudate and putamen nuclei compared to healthy controls * Higher magnetic susceptibility
Pharmacology
PMCID: PMC12178211 PMID: 40536830 DOI: 10.1111/adb.70058 Journal: Addiction biology Publication Date: 2025-6-19 Authors: Lovelock DF, Liu W, Hamida SB, Cordero VL, Van Voorhies KJ, et al. Key Points * RTI-122 demonstrates a selective, receptor-specific mechanism for reducing alcohol consumption across multiple experimental models * Significant reductions in alcohol intake
Pulmonology
PMCID: PMC12176163 PMID: 40531833 DOI: 10.1371/journal.pone.0326060 Journal: PloS one Publication Date: 2025-6-18 Authors: Liu N, Zhang Q, Wang H, Ding R, Geng X, et al. Key Points * Transpulmonary driving pressure >12.5 cmH2O is associated with increased mortality in ARDS patients * Targeted TPDP management reduced
Neurology
PMCID: PMC12173837 PMID: 40528277 DOI: 10.1002/alz.70361 Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association Publication Date: 2025-6-17 Authors: Goodwin GJ, Mehrzad S, Cummings JL, Renn BN, Kinney JW, et al. Key Points * Bridge symptoms differ markedly between AD and bvFTD, with
Gastroenterology
PMCID: PMC12174243 PMID: 40528089 DOI: 10.1007/s00384-025-04937-3 Journal: International journal of colorectal disease Publication Date: 2025-6-18 Authors: Mostafa OE, Zaman S, Malik M, Kumar P, Kumar L, et al. Key Points * No significant clinical advantage was observed with extended mesenteric resection compared to conventional resection in Crohn's
Immunology
PMCID: PMC12179044 PMID: 40536705 DOI: 10.1007/s00262-025-04091-3 Journal: Cancer immunology, immunotherapy : CII Publication Date: 2025-6-19 Authors: Gustafson AM, Dinerman AJ, Hitscherich KJ, Parkhurst MR, Halas H, et al. Key Points * Lung metastases demonstrated superior TIL growth (95%) compared to other resection sites * 51% of TIL harvests showed high neoantigen
Oncology
PMCID: PMC12173190 PMID: 40526592 DOI: 10.1371/journal.pone.0325667 Journal: PloS one Publication Date: 2025-6-17 Authors: Kimura N, Shirai Y, Itoh A, Hirano K, Shibuya K, et al. Key Points * Comprehensive multicenter study addressing optimal lymph node dissection in PDAC * Evaluating metastasis rates across different pancreatic tumor locations to
Emergency_Medicine
PMCID: PMC12170732 PMID: 40523996 DOI: 10.1007/s00431-025-06242-1 Journal: European journal of pediatrics Publication Date: 2025-6-17 Authors: Ito-Shinjo A, Shinjo D, Nakamura T, Kubota M, Fushimi K Key Points * Pediatric tracheostomy patients under 1 year old have significantly higher risks of readmission and emergency department visits * 43% of patients were
Pharmacology
PMCID: PMC12175699 PMID: 40526090 DOI: 10.18632/oncotarget.28744 Journal: Oncotarget Publication Date: 2025 Authors: Hernando-Calvo A, Kurzrock R, Gonzalez NS, Magidi S, Bresson C, et al. Key Points * Comprehensive molecular profiling revealed multiple actionable genetic alterations in mCRC * Personalized treatment strategies proposed, including targeted therapies matching specific mutations * Repeated
Pharmacology
PMCID: PMC12178431 PMID: 40525920 DOI: 10.1167/iovs.66.6.56 Journal: Investigative ophthalmology & visual science Publication Date: 2025-6-17 Authors: Ji R, Ishikawa K, Tan W, Mori K, Tsukamoto R, et al. Key Points * Liposomal encapsulation of ripasudil dramatically improves drug retention and targeted delivery in ocular tissues * Lipo-Ripa