Pharmacology
PMCID: PMC12178595 PMID: 40537054 DOI: 10.7189/jogh.15.04190 Journal: Journal of global health Publication Date: 2025-6-20 Authors: Tian F, Chen Z, Zhang Y, Feng Q Key Points * Overall PIP prevalence remained stable at approximately 29%, but multiple PIM-related prescriptions increased (AAPC = 4.45) * Sedative-hypnotic medications showed significant upward
Pharmacology
PMCID: PMC12175327 PMID: 40528159 DOI: 10.1186/s12951-025-03522-8 Journal: Journal of nanobiotechnology Publication Date: 2025-6-17 Authors: Su Y, Leng M, Yang Q, Jiang W, Xiang G, et al. Key Points * Neutrophil-CTC interactions are a critical mechanism driving cancer metastasis through multiple biological processes * Nanotechnology-based drug delivery systems show promise in
Surgery
PMCID: PMC12177007 PMID: 40531329 DOI: 10.1007/s00590-025-04372-8 Journal: European journal of orthopaedic surgery & traumatology : orthopedie traumatologie Publication Date: 2025-6-18 Authors: Liu SH, Leonardo CJ, Loyst RA, Konnayil BJ, Bramian A, et al. Key Points * Preoperative anemia is independently associated with increased 30-day postoperative complications in revision total shoulder
Anesthesiology
PMCID: PMC12172574 PMID: 40525838 DOI: 10.1111/scd.70031 Journal: Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry Publication Date: 2025-6-17 Authors: Delgado RZ, Bueno M, Mugayar L, Franco JB Key
Endocrinology
PMCID: PMC12177074 PMID: 40533477 DOI: 10.1038/s41387-025-00381-y Journal: Nutrition & diabetes Publication Date: 2025-6-18 Authors: Park S, Widmer A, Swartz AZ, Koethe JR, Silver HJ Key Points * PWH with diabetes showed significantly altered tissue densities, with 2.5-fold higher hepatic steatosis prevalence compared to those without diabetes * Myosteatosis was
Emergency_Medicine
PMCID: PMC12173181 PMID: 40526732 DOI: 10.1371/journal.pone.0326194 Journal: PloS one Publication Date: 2025-6-17 Authors: Sun M, Zhang X, Liu YC, Pei J, Fan H, et al. Key Points * OSA patients represent a distinct, high-acuity subgroup in emergency departments, with unique demographic and clinical characteristics * Adjusted odds ratios
Immunology
PMCID: PMC12177686 PMID: 40534591 DOI: 10.1002/eji.202451233 Journal: European journal of immunology Publication Date: 2025-6-19 Authors: Gjurgjaj A, Conde CD Key Points * Single-cell multiomics provides unprecedented insights into the molecular mechanisms underlying autoimmune diseases * Emerging computational integration and deep-learning tools show promise for disease stratification and drug prioritization
Surgery
PMCID: PMC12175424 PMID: 40533860 DOI: 10.1186/s41065-025-00479-4 Journal: Hereditas Publication Date: 2025-6-18 Authors: Wu X, Cai R, Ye M, Yang X, Sun D, et al. Key Points * Ilizarov periosteal distraction provides a novel mechanotherapeutic approach for AVM-related ischemic ulcers * 75% wound epithelialization achieved within 4 weeks of intervention * Offers
Emergency_Medicine
PMCID: PMC12177648 PMID: 40531532 DOI: 10.1001/jamanetworkopen.2025.16582 Journal: JAMA network open Publication Date: 2025-6-18 Authors: Ouchi K, Block SD, Rentz DM, Berry DL, Oelschlager H, et al. Key Points * Nurse-led ED intervention increased clinician-documented serious illness conversations without significant patient-reported engagement * Clinician documentation of SICs increased from
Immunology
PMCID: PMC12175482 PMID: 40530896 DOI: 10.1002/cam4.70994 Journal: Cancer medicine Publication Date: 2025-6-18 Authors: Wang F, Chen W, Jia Y, He T, Wu S, et al. Key Points * Intestinal microbiota significantly modulates immunotherapy response in colorectal cancer * Specific bacterial strains can enhance CD8+ T cell infiltration and cytotoxicity
Pharmacology
PMCID: PMC12172391 PMID: 40525645 DOI: 10.1111/eip.70063 Journal: Early intervention in psychiatry Publication Date: 2025-6-17 Authors: Ward TM, Xu J, Hall DB, Chen X, Benavides S, et al. Key Points * LAI antipsychotics represent an emerging treatment strategy for pediatric psychiatric populations, potentially improving medication adherence * Paliperidone palmitate showed
Pharmacology
PMCID: PMC12170901 PMID: 40523897 DOI: 10.1038/s41392-025-02274-z Journal: Signal transduction and targeted therapy Publication Date: 2025-6-17 Authors: Ruan DY, Wu HX, Xu Y, Munster PN, Deng Y, et al. Key Points * First study with the highest proportion of Asian mCRC patients receiving a KRAS G12C inhibitor, demonstrating promising anti-tumor