Ethan Littlefield - CurrentMed (Page 19)

Radiology

Deep learning detects retropharyngeal edema on MRI in patients with acute neck infections

PMCID: PMC12179047 PMID: 40536731 DOI: 10.1186/s41747-025-00599-6 Journal: European radiology experimental Publication Date: 2025-6-19 Authors: Rainio O, Huhtanen H, Vierula JP, Nurminen J, Heikkinen J, et al. Key Points * Deep learning algorithm achieved 87.4% accuracy in detecting retropharyngeal edema at the patient level * AUROC values of 94.8%

Infectious_Disease

Infection Spread and Outbreaks Support with Spatial-Temporal Visualization Tool for Hospitals

PMCID: PMC12176923 PMID: 40531282 DOI: 10.1007/s10916-025-02219-7 Journal: Journal of medical systems Publication Date: 2025-6-18 Authors: Kim D, Canovas-Segura B, Campos M, Aleman Belando S, Juarez JM Key Points * Interactive visualization provides a novel method for tracking hospital-acquired infections across spatial and temporal dimensions * User evaluation showed 91.43%

Pulmonology

Diagnostic Use of CCR3, CD63, CD203c and FcεRIα on Blood Leukocytes of Allergic Asthma and Combined Allergic Rhinitis and Asthma Syndrome

PMCID: PMC12176697 PMID: 40534099 DOI: 10.1111/jcmm.70594 Journal: Journal of cellular and molecular medicine Publication Date: 2025-6-18 Authors: Wang J, Zhan M, Gu F, Zhang H, Xie H, et al. Key Points * CCR3+ cell numbers and marker expressions are significantly altered in allergic asthma and allergic rhinitis patients

Immunology

Mutation in the rat interleukin 34 gene impacts macrophage development, homeostasis, and inflammation

PMCID: PMC12177736 PMID: 40533345 DOI: 10.26508/lsa.202503264 Journal: Life science alliance Publication Date: 2025-6-18 Authors: Huang S, Patkar OL, Schulze S, Carter-Cusack D, Millard S, et al. Key Points * IL34 deficiency leads to selective microglial depletion in grey matter brain regions * Heterozygous Il34+/- rats demonstrate partial loss

Psychiatry

Transcranial Electrical Stimulation in Treatment of Depression: A Systematic Review and Meta-Analysis

PMCID: PMC12177679 PMID: 40531534 DOI: 10.1001/jamanetworkopen.2025.16459 Journal: JAMA network open Publication Date: 2025-6-18 Authors: Ren C, Pagali SR, Wang Z, Kung S, Boyapati RB, et al. Key Points * tDCS combined with medication showed significant improvement in depression with comorbid conditions * tACS demonstrated improved depressive symptoms in

Infectious_Disease

Vaccine fatigue and influenza vaccination trends across Pre-, Peri-, and Post-COVID-19 periods in the United States using epic’s cosmos database

PMCID: PMC12173228 PMID: 40526617 DOI: 10.1371/journal.pone.0326098 Journal: PloS one Publication Date: 2025-6-17 Authors: Nofzinger TB, Huang TT, Lingat CE, Amonkar GM, Edwards EE, et al. Key Points * Overall influenza vaccination rates decreased by 6.41 percentage points post-COVID-19 * Youngest age groups (5-18 and 19-26 years) experienced

Radiology

Advancing Tumor Budding Detection With Fourier Ptychography Microscopy

PMCID: PMC12175198 PMID: 40530892 DOI: 10.1002/cam4.70989 Journal: Cancer medicine Publication Date: 2025-6-18 Authors: Su Y, Sun R, Wang Y, xi Y, Zhang S Key Points * FPM enables digital refocusing and marker removal without physical slide manipulation * 100% diagnostic accuracy achieved using a simplified microscopy approach * Potential to

Immunology

ORM1 Mediates Ln-IgG-Induced Podocyte Damage and Autophagy via the AMPK/mTOR Signaling

PMCID: PMC12184165 PMID: 40526157 DOI: 10.1080/15476278.2025.2519614 Journal: Organogenesis Publication Date: 2025-6-17 Authors: Chen J, Zou L, Liu L, Wu C, Hu M Key Points * ORM1 plays a critical role in podocyte damage and autophagy in lupus nephritis * ORM1 knockdown increased podocyte viability by approximately 40% and

Oncology

PI3K-dependent GAB1/Erk phosphorylation renders head and neck squamous cell carcinoma sensitive to PI3Kα inhibitors

PMCID: PMC12177050 PMID: 40533463 DOI: 10.1038/s41419-025-07767-x Journal: Cell death & disease Publication Date: 2025-6-18 Authors: Zhang X, Xu J, Wang X, Xu L, Zhang X, et al. Key Points * CYH33 demonstrates potent anti-proliferative activity against HNSCC, including cisplatin-resistant cell lines * Achieved significant tumor growth inhibition in xenograft models

Neurology

p‐Cresol and p‐Cresyl Sulphate Boost Oxidative Stress: A Systematic Review of Recent Evidence

PMCID: PMC12177445 PMID: 40534235 DOI: 10.1111/bcpt.70065 Journal: Basic & clinical pharmacology & toxicology Publication Date: 2025-6-18 Authors: Renaldi R, Wiguna T, Persico AM, Tanra AJ Key Points * p-Cresol and PCS induce oxidative stress through NADPH oxidase activation, with potential implications for neurological and metabolic disorders * Concentrations as

Oncology

The impact of de novo lipogenesis on predicting survival and clinical therapy: an exploration based on a multigene prognostic model in hepatocellular carcinoma

PMCID: PMC12178006 PMID: 40533802 DOI: 10.1186/s12967-025-06704-y Journal: Journal of translational medicine Publication Date: 2025-6-18 Authors: Zhou X, Cui G, Hu E, Wang X, Tang D, et al. Key Points * A six-gene DNL signature effectively stratifies HCC patients into distinct prognostic risk groups * Predictive model shows high accuracy with

Oncology

ESRP1 exerts anti-tumor role by promoting ferroptosis in diffuse-type gastric cancer

PMCID: PMC12175430 PMID: 40528239 DOI: 10.1186/s13046-025-03435-2 Journal: Journal of experimental & clinical cancer research : CR Publication Date: 2025-6-18 Authors: Xu K, Chen H, Zhu X, Li H, Liu X, et al. Key Points * High ESRP1 expression is an independent prognostic factor for improved survival in diffuse-type gastric cancer