Surgery

Risk factors for ACL revision failure and optimum graft size for revision anterior cruciate ligament reconstruction

Ethan Littlefield

05 Jul 2025 — 1 min read

PMCID: PMC12179230

PMID: 40536685

DOI: 10.1007/s00590-025-04381-7

Journal: European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

Publication Date: 2025-6-19

Authors: Lu VY, Lee DH, Tsui SH, Lo TC, Chau WW, et al.

Key Points

Graft diameter < 9 mm significantly increases re-rupture risk in revision ACLR
16.7% of revision ACLR patients experienced graft re-rupture
Surgeons should carefully counsel patients about return to pivoting sports after revision surgery

Summary

This retrospective study investigated risk factors for graft re-rupture after revision anterior cruciate ligament reconstruction (ACLR), focusing on the critical clinical challenge of graft failure in secondary surgical interventions. Among 132 patients undergoing revision ACLR, the overall graft re-rupture rate was 16.7%, with a mean follow-up of 3.22 years. The research specifically examined how graft diameter and return to pivoting sports might influence re-injury risk.

Multivariate logistic regression analysis revealed two significant independent risk factors for graft re-rupture: graft diameter < 9 mm (OR: 3.873; 95% CI 1.128–13.293; p=0.031) and return to pivoting sports after revision surgery (OR: 4.105; 95% CI 1.008–16.721; p=0.049). Notably, contrary to potential expectations, concomitant knee pathologies such as meniscal or chondral lesions were not associated with increased re-rupture rates. These findings provide nuanced insights for surgeons planning revision ACLR, emphasizing the importance of graft sizing and patient activity modification.

Status and associated factors of psychological resilience of Chinese medical aid team members under public health emergencies in a cross-sectional study

PMCID: PMC12173397 PMID: 40526630 DOI: 10.1371/journal.pone.0324952 Journal: PloS one Publication Date: 2025-6-17 Authors: Wei X, Liang Y, Huang J Key Points * Psychological resilience is significantly influenced by professional experience, family support, and cultural adaptation * 53.9% of CMATMs reported experiencing loneliness, which negatively impacted psychological resilience

Structured light imaging mesoscopy: detection of embedded morphological changes in superficial tissues

PMCID: PMC12175002 PMID: 40534904 DOI: 10.1117/1.JBO.30.6.065001 Journal: Journal of biomedical optics Publication Date: 2025-6-18 Authors: Parsanasab M, Mehendale AM, Karrobi K, Roblyer D, Venugopalan V Key Points * SLIM provides a novel, non-invasive method for detecting subsurface tissue microstructural changes * Optimal imaging parameters vary significantly

Experimental evolution of a pathogen confronted with innate immune memory increases variation in virulence

PMCID: PMC12176410 PMID: 40532126 DOI: 10.1371/journal.ppat.1012839 Journal: PLoS pathogens Publication Date: 2025-6-18 Authors: Korša A, Baur M, Schulz NK, Anaya-Rojas JM, Mellmann A, et al. Key Points * Immune priming creates selective pressure that increases pathogen virulence variability without compromising host defense mechanisms * 96.6% probability of

Long‐Term or Recurrent Antibiotic Use in Early Life and the Risk of Type 2 Diabetes: A Population‐Based Prospective Cohort and a Case–Control Study

PMCID: PMC12176498 PMID: 40533417 DOI: 10.1111/1753-0407.70113 Journal: Journal of diabetes Publication Date: 2025-6-18 Authors: Li Z, He Q, He X, Xing X, Fu S, et al. Key Points * Long-term or recurrent antibiotic use during childhood may significantly increase type 2 diabetes risk * 26% higher hazard ratio for